The First Meeting of the Eureka Student Research Club in the 2026–2027 Academic Year

The Department of Pathological Physiology, Pharmacology and Pharmacotherapy held another meeting of the Eureka Student Research Club, bringing students together to explore current issues in modern medicine, pathological physiology and pharmacology.

The meeting was attended by 36 students enrolled in the Medicine and Dentistry degree programmes. They had the opportunity to learn about student research findings, discuss current scientific questions and take part in a professional discussion. The presentations sparked lively interest among the audience and received positive feedback.

The topics covered a broad range of issues, from how medicines cross the blood–brain barrier to the genetic mechanisms underlying disease, pharmacogenetics and the personalisation of drug therapy.

Six research presentations were delivered:

Oleksandra Zaiarna — “The Role of the Blood–Brain Barrier in Limiting the Effectiveness of Drug Treatment for Brain Tumours.”

Kira Draienko — “Genetic Factors Predisposing to the Recurrence of Varicose Veins: The Role of PIEZO1 Gene Polymorphism.”

Inna Kripak — “The Role of Genetic Polymorphisms in Drug Biotransformation Enzymes in Personalising Pharmacotherapy for Dental Patients.”

Alina Hurkalo and Polina Ilienko — “Mechanisms of Dose-Dependent and Dose-Independent Adverse Drug Reactions: Implications for Personalised Pharmacotherapy in Dentistry.”

Mariana Karpenko — “Pharmacological Mechanisms of the Effects of Anti-Inflammatory Drugs on Periodontal Tissues and Opportunities for Individualising Therapy.”

Vladyslava Honcharuk — “Pharmacological Mechanisms of Interactions Between Non-Steroidal Anti-Inflammatory Drugs and Anticoagulants: Individualising the Assessment of Bleeding Risk.”

The Eureka Student Research Club is led by Iryna Tymchenko, Head of the Department of Pathological Physiology, Pharmacology and Pharmacotherapy, Candidate of Medical Sciences and Associate Professor. She supervised the students’ research, guiding them in their in-depth study of pathophysiological mechanisms, pharmacological principles and contemporary approaches to individualising treatment.

Kira Draienko’s research experience deserves special mention. Her work on genetic factors associated with the recurrence of varicose veins included original experimental research at the O.O. Bogomolets Institute of Physiology of the National Academy of Sciences of Ukraine, under the scientific supervision of Serhii Viktorovych Honcharov. This gave her the opportunity to take part in hands-on experimental research and present the findings of her own scientific inquiry.

The meeting provided a forum for discussing recent scientific publications, analysing the mechanisms of pathological processes, evaluating the evidence for pharmacological approaches and exploring how they may be applied in clinical practice.

The presentations reflected the students’ interest in research, their commitment to independently analysing complex biomedical questions and their understanding of the importance of a personalised approach to pharmacotherapy.

The Eureka Student Research Club continues to bring together students with an interest in research, creating opportunities to develop research skills, exchange ideas and prepare future professionals to connect foundational knowledge with the practical challenges of medicine.